Hey, I think this is a great resource and really helpful. I was looking at the recommended reading section and saw a section on "Phasing" that referenced the Brownings' Paper "Haplotype phasing: existing methods and new developments". This paper is great and does a good job explaining the benefits of statistical phasing. There is a newer review article from nature "Haplotype phasing: existing methods and new developments" by Sun & Li (doi: https://doi.org/10.1038/s41576-025-00895-2). This paper goes over the current state of phasing with modern tools like SHAPEIT5 that use different statistically approaches like a hidden Markov model for efficient. It also dives a little more into the use of phasing in imputation, phasing rare variants, and how phasing can be used with WGS since the field has shifted more to those technologies in the past decade.
Question
Do you think it would be beneficial to people to also add this article to the Phasing section of the recommended reading? Having both the Brownings' original 2011 publication and the new one gives people the foundation for statistical phasing as well as an introduction to modern tooling.
Thanks again for all your work on this!
Hey, I think this is a great resource and really helpful. I was looking at the recommended reading section and saw a section on "Phasing" that referenced the Brownings' Paper "Haplotype phasing: existing methods and new developments". This paper is great and does a good job explaining the benefits of statistical phasing. There is a newer review article from nature "Haplotype phasing: existing methods and new developments" by Sun & Li (doi: https://doi.org/10.1038/s41576-025-00895-2). This paper goes over the current state of phasing with modern tools like SHAPEIT5 that use different statistically approaches like a hidden Markov model for efficient. It also dives a little more into the use of phasing in imputation, phasing rare variants, and how phasing can be used with WGS since the field has shifted more to those technologies in the past decade.
Question
Do you think it would be beneficial to people to also add this article to the Phasing section of the recommended reading? Having both the Brownings' original 2011 publication and the new one gives people the foundation for statistical phasing as well as an introduction to modern tooling.
Thanks again for all your work on this!