diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 6d5d84a71..e06a0e4e6 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -14,7 +14,7 @@ jobs:
     runs-on: ubuntu-latest
     strategy:
       matrix:
-        python-version: ["3.10", "3.11", "3.12"]
+        python-version: ["3.11", "3.12", "3.13", "3.14"]
     services:
       mariadb:
         image: mariadb:12.2.2 # released 2024-05-06
diff --git a/.github/workflows/publish-version.yml b/.github/workflows/publish-version.yml
index 520996828..c19816cd6 100644
--- a/.github/workflows/publish-version.yml
+++ b/.github/workflows/publish-version.yml
@@ -17,10 +17,10 @@ jobs:
       newVersion: ${{ steps.checkTag.outputs.newVersion }}
     steps:
       - uses: actions/checkout@v6
-      - name: Use Python 3.10
+      - name: Use Python 3.14
         uses: actions/setup-python@v6
         with:
-          python-version: "3.10"
+          python-version: "3.14"
       - name: Check current tag
         id: checkTag
         run: |
@@ -65,10 +65,10 @@ jobs:
     if: ${{ needs.get-current-version.outputs.doTag == 'true' }}
     steps:
       - uses: actions/checkout@v6
-      - name: Set up Python 3.10
+      - name: Set up Python 3.14
         uses: actions/setup-python@v6
         with:
-          python-version: "3.10"
+          python-version: "3.14"
       - name: Install pypa/build
         run: >-
           python3 -m
diff --git a/.github/workflows/test.yml b/.github/workflows/test.yml
index bcf26da33..bd87bc69d 100644
--- a/.github/workflows/test.yml
+++ b/.github/workflows/test.yml
@@ -21,10 +21,10 @@ jobs:
     runs-on: ubuntu-latest
     steps:
       - uses: actions/checkout@v6
-      - name: Set up Python 3.10
+      - name: Set up Python 3.14
         uses: actions/setup-python@v6
         with:
-          python-version: "3.10"
+          python-version: "3.14"
       - name: Syntax validation
         run: |
           python .github/workflows/scripts/syntax-validation.py
@@ -38,10 +38,10 @@ jobs:
     runs-on: ubuntu-latest
     steps:
       - uses: actions/checkout@v6
-      - name: Set up Python 3.10
+      - name: Set up Python 3.14
         uses: actions/setup-python@v6
         with:
-          python-version: "3.10"
+          python-version: "3.14"
       - name: Install pypa/build
         run: >-
           python3 -m
diff --git a/.github/workflows/version-bump.yml b/.github/workflows/version-bump.yml
index aeef9c2d9..2e751dacb 100644
--- a/.github/workflows/version-bump.yml
+++ b/.github/workflows/version-bump.yml
@@ -35,10 +35,10 @@ jobs:
       pull-requests: write
     steps:
       - uses: actions/checkout@v6
-      - name: Set up Python 3.10
+      - name: Set up Python 3.14
         uses: actions/setup-python@v6
         with:
-          python-version: "3.10"
+          python-version: "3.14"
       - name: Install package
         run: |
           set -eux
diff --git a/Dockerfiles/murfey-instrument-server b/Dockerfiles/murfey-instrument-server
index b3c50b894..1196889a4 100644
--- a/Dockerfiles/murfey-instrument-server
+++ b/Dockerfiles/murfey-instrument-server
@@ -38,7 +38,7 @@ RUN \
     /venv/bin/python -m pip install --upgrade \
         pip \
         build \
-        importlib-metadata && \
+        && \
     /venv/bin/python -m pip install /tmp/python-murfey[sxt]
 
 
diff --git a/Dockerfiles/murfey-server b/Dockerfiles/murfey-server
index 2cbf18a5d..b5abcbb7b 100644
--- a/Dockerfiles/murfey-server
+++ b/Dockerfiles/murfey-server
@@ -37,8 +37,7 @@ RUN \
     /venv/bin/python -m pip install --upgrade \
         pip \
         build \
-        importlib-metadata \
-        psycopg2-binary && \
+        && \
     /venv/bin/python -m pip install /tmp/python-murfey[server] && \
     echo "Installing IMOD..." && \
     mkdir /imod && \
diff --git a/pyproject.toml b/pyproject.toml
index 375438c22..e2742a176 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -16,7 +16,7 @@ keywords = [
 license = {file = "LICENSE"}
 maintainers = []
 authors = []
-requires-python = ">=3.10"
+requires-python = ">=3.11"
 classifiers = [
     "Development Status :: 3 - Alpha",
     "Environment :: Console",
@@ -24,9 +24,10 @@ classifiers = [
     "License :: OSI Approved :: BSD License",
     "Operating System :: OS Independent",
     "Programming Language :: Python :: 3 :: Only",
-    "Programming Language :: Python :: 3.10",
     "Programming Language :: Python :: 3.11",
     "Programming Language :: Python :: 3.12",
+    "Programming Language :: Python :: 3.13",
+    "Programming Language :: Python :: 3.14",
 ]
 dependencies = [
     "aiohttp",
@@ -64,7 +65,7 @@ server = [
     "passlib",
     "pillow",
     "prometheus_client",
-    "sqlalchemy[postgresql]", # Add as explicit dependency
+    "sqlalchemy[postgresql]>=2.1.0",
     "sqlmodel",
     "stomp-py>8.1.1", # 8.1.1 (released 2024-04-06) doesn't work with our project
     "zocalo>=1",
@@ -168,7 +169,7 @@ inputs = "pyproject.toml"
 check = false
 indent = 4
 keep_full_version = true
-max-supported-python = "3.12"
+max_supported_python = "3.14"
 
 [tool.pytest.ini_options]
 addopts = "-ra"
diff --git a/src/murfey/server/murfey_db.py b/src/murfey/server/murfey_db.py
index 3efd156f3..0a52f794a 100644
--- a/src/murfey/server/murfey_db.py
+++ b/src/murfey/server/murfey_db.py
@@ -41,7 +41,7 @@ def url(security_config: Security | None = None) -> str:
         return f"sqlite:///{creds['database']}"
     f = Fernet(security_config.crypto_key.encode("ascii"))
     p = f.decrypt(creds["password"].encode("ascii"))
-    return f"postgresql+psycopg2://{creds['username']}:{p.decode()}@{creds['host']}:{creds['port']}/{creds['database']}"
+    return f"postgresql://{creds['username']}:{p.decode()}@{creds['host']}:{creds['port']}/{creds['database']}"
 
 
 def get_murfey_db_session(
diff --git a/tests/conftest.py b/tests/conftest.py
index 69cbd8363..74cc4bbfa 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -306,7 +306,7 @@ def ispyb_db_session(
 def murfey_db_url():
     try:
         return (
-            f"postgresql+psycopg2://{os.environ['POSTGRES_USER']}:{os.environ['POSTGRES_PASSWORD']}"
+            f"postgresql://{os.environ['POSTGRES_USER']}:{os.environ['POSTGRES_PASSWORD']}"
             f"@{os.environ['POSTGRES_HOST']}:{os.environ['POSTGRES_PORT']}/{os.environ['POSTGRES_DB']}"
         )
     # Skip Murfey database-related tests if the environment for it hasn't been set up