diff --git a/test/autoconf/configure.ac b/test/autoconf/configure.ac
new file mode 100644
index 0000000000000..4d061d87b673d
--- /dev/null
+++ b/test/autoconf/configure.ac
@@ -0,0 +1,10 @@
+AC_INIT([test], [1.0])
+AC_PROG_CC
+AC_CHECK_FUNCS([getcwd getwd nonexistent_func])
+AC_CHECK_HEADERS([stdio.h nonexistent_header.h])
+AC_RUN_IFELSE([AC_LANG_PROGRAM([[#include <stdio.h>]], [[return 0;]])],
+              [run_ok=yes], [run_ok=no])
+AS_IF([test "x$run_ok" = xyes],
+      [AC_MSG_NOTICE([run test passed])],
+      [AC_MSG_ERROR([run test failed])])
+AC_OUTPUT
diff --git a/test/test_other.py b/test/test_other.py
index 856d84a72191f..4626e9ba46375 100644
--- a/test/test_other.py
+++ b/test/test_other.py
@@ -12518,6 +12518,18 @@ def test_autoconf_check_lib_side_module(self):
     ''')
     self.run_process([EMCC, 'conftest.c', 'libtest.so', '-o', 'conftest.js'])
 
+  @no_windows('configure scripts are Unix shell scripts')
+  @requires_tool('autoconf')
+  def test_autoconf_configure(self):
+    copytree(test_file('autoconf'), '.')
+    self.run_process(['autoconf'])
+    out = self.run_process([EMCONFIGURE, './configure'], stdout=PIPE).stdout
+    self.assertContained('checking for getcwd... yes', out)
+    self.assertContained('checking for getwd... no', out)
+    self.assertContained('checking for nonexistent_func... no', out)
+    self.assertContained('checking for nonexistent_header.h... no', out)
+    self.assertContained('configure: run test passed', out)
+
   def test_standalone_export_main(self):
     # Tests that explicitly exported `_main` does not fail, even though `_start` is the entry
     # point.