diff --git a/CHANGELOG.md b/CHANGELOG.md
index 496c5333ec..94cdeea85a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -4,6 +4,8 @@
 
 ### Fixes
 
+- Keep UI profiling running when `startProfiler` is called before a requested stop takes effect at the end of the current chunk ([#6291](https://github.com/getsentry/sentry-java/pull/6291))
+  - Before, the start call was ignored and the profiler still stopped at the end of the chunk, even in `TRACE` mode while sampled spans were active. On API 34 and lower, every later profile also stopped after one chunk.
 - Keep sending events from Android 7.1.0 and older devices after Sentry changes its TLS certificate authority ([#6227](https://github.com/getsentry/sentry-java/pull/6227))
   - In February 2027, Sentry moves its TLS certificates from DigiCert to Let's Encrypt and Google Trust Services ([announcement](https://sentry.io/changelog/were-changing-our-tls-certificate-authority-in-february-2027)).
   - Android 7.1.0 (API 25) and older don't trust the Let's Encrypt root certificate (ISRG Root X1), so without this fix, the SDK on those devices can no longer send events to Sentry after the switch.
diff --git a/sentry-android-core/src/main/java/io/sentry/android/core/AndroidContinuousProfiler.java b/sentry-android-core/src/main/java/io/sentry/android/core/AndroidContinuousProfiler.java
index 20fea39a28..4f115ca9d7 100644
--- a/sentry-android-core/src/main/java/io/sentry/android/core/AndroidContinuousProfiler.java
+++ b/sentry-android-core/src/main/java/io/sentry/android/core/AndroidContinuousProfiler.java
@@ -131,6 +131,8 @@ public void startProfiler(
         logger.log(SentryLevel.DEBUG, "Profiler was not started due to sampling decision.");
         return;
       }
+      // A stop only takes effect when the current chunk ends, so a start before then cancels it.
+      shouldStop = false;
       switch (profileLifecycle) {
         case TRACE:
           // rootSpanCounter should never be negative, unless the user changed profile lifecycle
diff --git a/sentry-android-core/src/main/java/io/sentry/android/core/PerfettoContinuousProfiler.java b/sentry-android-core/src/main/java/io/sentry/android/core/PerfettoContinuousProfiler.java
index 58065c708e..15ae88f22c 100644
--- a/sentry-android-core/src/main/java/io/sentry/android/core/PerfettoContinuousProfiler.java
+++ b/sentry-android-core/src/main/java/io/sentry/android/core/PerfettoContinuousProfiler.java
@@ -141,6 +141,8 @@ public void startProfiler(
         logger.log(SentryLevel.DEBUG, "Profiler was not started due to sampling decision.");
         return;
       }
+      // A stop only takes effect when the current chunk ends, so a start before then cancels it.
+      shouldStop = false;
       switch (profileLifecycle) {
         case TRACE:
           activeTraceCount = Math.max(0, activeTraceCount); // safety check.
@@ -148,16 +150,13 @@ public void startProfiler(
           break;
         case MANUAL:
           if (isRunning()) {
-            logger.log(
-                SentryLevel.WARNING,
-                "Unexpected call to startProfiler(MANUAL) while profiler already running. Skipping.");
+            logger.log(SentryLevel.DEBUG, "Profiler is already running.");
             return;
           }
           break;
       }
       if (!isRunning()) {
         logger.log(SentryLevel.DEBUG, "Started Profiler.");
-        shouldStop = false;
         startInternal();
       }
     }
diff --git a/sentry-android-core/src/test/java/io/sentry/android/core/AndroidContinuousProfilerTest.kt b/sentry-android-core/src/test/java/io/sentry/android/core/AndroidContinuousProfilerTest.kt
index caaa30152a..a13f3fe124 100644
--- a/sentry-android-core/src/test/java/io/sentry/android/core/AndroidContinuousProfilerTest.kt
+++ b/sentry-android-core/src/test/java/io/sentry/android/core/AndroidContinuousProfilerTest.kt
@@ -278,6 +278,18 @@ class AndroidContinuousProfilerTest {
       }
       .testDoesNotStartWhenOffline(mocks)
 
+  @Test
+  fun `manual start cancels a pending stop`() =
+    fixture.getSut().testManualStartCancelsPendingStop(mocks)
+
+  @Test
+  fun `trace start cancels a pending stop`() =
+    fixture.getSut().testTraceStartCancelsPendingStop(mocks)
+
+  @Test
+  fun `manual profiler can be started again after a full start-stop cycle`() =
+    fixture.getSut().testCanBeStartedAgainAfterStopCycle(mocks)
+
   // -- Legacy-specific tests (AndroidContinuousProfiler only) --
 
   @Test
diff --git a/sentry-android-core/src/test/java/io/sentry/android/core/ContinuousProfilerTestCases.kt b/sentry-android-core/src/test/java/io/sentry/android/core/ContinuousProfilerTestCases.kt
index 5e4e0504dd..267529fd33 100644
--- a/sentry-android-core/src/test/java/io/sentry/android/core/ContinuousProfilerTestCases.kt
+++ b/sentry-android-core/src/test/java/io/sentry/android/core/ContinuousProfilerTestCases.kt
@@ -192,3 +192,23 @@ fun IContinuousProfiler.testCanBeStartedAgainAfterStopCycle(mocks: ProfilerMocks
   mocks.executor.runAll()
   assertTrue(isRunning, "shouldStop must be reset on start")
 }
+
+fun IContinuousProfiler.testManualStartCancelsPendingStop(mocks: ProfilerMocks) {
+  startProfiler(ProfileLifecycle.MANUAL, mocks.tracesSampler)
+  val profilerIdBeforeStop = profilerId
+  stopProfiler(ProfileLifecycle.MANUAL)
+  startProfiler(ProfileLifecycle.MANUAL, mocks.tracesSampler)
+  mocks.executor.runAll()
+  assertTrue(isRunning, "a start before the chunk ends must cancel the pending stop")
+  assertEquals(profilerIdBeforeStop, profilerId)
+}
+
+fun IContinuousProfiler.testTraceStartCancelsPendingStop(mocks: ProfilerMocks) {
+  startProfiler(ProfileLifecycle.TRACE, mocks.tracesSampler)
+  val profilerIdBeforeStop = profilerId
+  stopProfiler(ProfileLifecycle.TRACE)
+  startProfiler(ProfileLifecycle.TRACE, mocks.tracesSampler)
+  mocks.executor.runAll()
+  assertTrue(isRunning, "a start before the chunk ends must cancel the pending stop")
+  assertEquals(profilerIdBeforeStop, profilerId)
+}
diff --git a/sentry-android-core/src/test/java/io/sentry/android/core/PerfettoContinuousProfilerTest.kt b/sentry-android-core/src/test/java/io/sentry/android/core/PerfettoContinuousProfilerTest.kt
index d6f29b97b7..3bafc29be3 100644
--- a/sentry-android-core/src/test/java/io/sentry/android/core/PerfettoContinuousProfilerTest.kt
+++ b/sentry-android-core/src/test/java/io/sentry/android/core/PerfettoContinuousProfilerTest.kt
@@ -178,6 +178,14 @@ class PerfettoContinuousProfilerTest {
   fun `manual profiler can be started again after a full start-stop cycle`() =
     fixture.getSut().testCanBeStartedAgainAfterStopCycle(mocks)
 
+  @Test
+  fun `manual start cancels a pending stop`() =
+    fixture.getSut().testManualStartCancelsPendingStop(mocks)
+
+  @Test
+  fun `trace start cancels a pending stop`() =
+    fixture.getSut().testTraceStartCancelsPendingStop(mocks)
+
   // -- Perfetto-specific tests --
 
   @Test
@@ -503,10 +511,6 @@ class PerfettoContinuousProfilerTest {
     assertTrue(profiler.isRunning)
     profiler.startProfiler(ProfileLifecycle.MANUAL, fixture.mockTracesSampler)
     assertTrue(profiler.isRunning)
-    verify(fixture.mockLogger)
-      .log(
-        eq(SentryLevel.WARNING),
-        eq("Unexpected call to startProfiler(MANUAL) while profiler already running. Skipping."),
-      )
+    verify(fixture.mockLogger).log(eq(SentryLevel.DEBUG), eq("Profiler is already running."))
   }
 }