diff --git a/.speakeasy/gen.yaml b/.speakeasy/gen.yaml
index 108cb297..9ca3ee6b 100644
--- a/.speakeasy/gen.yaml
+++ b/.speakeasy/gen.yaml
@@ -39,7 +39,7 @@ python:
       types-python-jose: ^3.4.0.20250224
     main:
       PyJWT: ^2.10.1
-      cryptography: ^49.0.0
+      cryptography: ^50.0.1
       python-jose: ^3.4.0
   allowedRedefinedBuiltins:
     - id
diff --git a/pyproject.toml b/pyproject.toml
index 7802173a..17265e15 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -8,7 +8,7 @@ readme = "README-PYPI.md"
 requires-python = ">=3.10"
 dependencies = [
     "PyJWT (>=2.10.1,<3.0.0)",
-    "cryptography (>=49.0.0,<50.0.0)",
+    "cryptography (>=50.0.1,<51.0.0)",
     "httpcore >=1.0.9",
     "httpx >=0.28.1",
     "jsonpath-python >=1.0.6",