diff --git a/core/src/components/alert/alert.tsx b/core/src/components/alert/alert.tsx
index de8d7bd450d..27095b1326f 100644
--- a/core/src/components/alert/alert.tsx
+++ b/core/src/components/alert/alert.tsx
@@ -238,15 +238,6 @@ export class Alert implements ComponentInterface, OverlayInterface {
   onKeydown(ev: any) {
     const inputTypes = new Set(this.processedInputs.map((i) => i.type));
 
-    /**
-     * Based on keyboard navigation requirements, the
-     * checkbox should not respond to the enter keydown event.
-     */
-    if (inputTypes.has('checkbox') && ev.key === 'Enter') {
-      ev.preventDefault();
-      return;
-    }
-
     /**
      * Ensure when alert container is being focused, and the user presses the tab + shift keys, the focus will be set to the last alert button.
      */
@@ -525,6 +516,15 @@ export class Alert implements ComponentInterface, OverlayInterface {
     forceUpdate(this);
   }
 
+  /**
+   * Prevent Enter from toggling the checkbox, which only Space should do.
+   */
+  private onCheckboxKeydown = (ev: KeyboardEvent) => {
+    if (ev.key === 'Enter') {
+      ev.preventDefault();
+    }
+  };
+
   private async buttonClick(button: AlertButton) {
     const role = button.role;
     const values = this.getValues();
@@ -625,6 +625,7 @@ export class Alert implements ComponentInterface, OverlayInterface {
             <button
               type="button"
               onClick={() => this.cbClick(i)}
+              onKeyDown={this.onCheckboxKeydown}
               aria-checked={`${i.checked}`}
               id={i.id}
               disabled={i.disabled}
diff --git a/core/src/components/alert/test/a11y/alert.e2e.ts b/core/src/components/alert/test/a11y/alert.e2e.ts
index 50a39fdccf0..cd5a7449c82 100644
--- a/core/src/components/alert/test/a11y/alert.e2e.ts
+++ b/core/src/components/alert/test/a11y/alert.e2e.ts
@@ -205,6 +205,69 @@ configs({ directions: ['ltr'] }).forEach(({ config, title }) => {
   });
 });
 
+/**
+ * This behavior does not vary across modes/directions
+ */
+configs({ modes: ['md'], directions: ['ltr'] }).forEach(({ title, config }) => {
+  test.describe(title('alert: Enter key with checkbox inputs'), () => {
+    test('should not block Enter in elements outside of the alert', async ({ page }, testInfo) => {
+      testInfo.annotations.push({
+        type: 'issue',
+        description: 'https://github.com/ionic-team/ionic-framework/issues/30811',
+      });
+
+      await page.setContent(
+        `
+        <textarea></textarea>
+        <ion-alert header="Alert"></ion-alert>
+
+        <script>
+          const alert = document.querySelector('ion-alert');
+          alert.inputs = [{ type: 'checkbox', label: 'Checkbox', value: 'checkbox' }];
+        </script>
+      `,
+        config
+      );
+
+      // The alert isn't presented since it would trap focus away from the textarea
+      const textarea = page.locator('textarea');
+      await textarea.click();
+      await textarea.press('a');
+      await textarea.press('Enter');
+      await textarea.press('b');
+
+      await expect(textarea).toHaveValue('a\nb');
+    });
+
+    test('should dismiss the alert when pressing Enter on a button', async ({ page }) => {
+      await page.setContent(
+        `
+        <ion-alert header="Alert"></ion-alert>
+
+        <script>
+          const alert = document.querySelector('ion-alert');
+          alert.inputs = [{ type: 'checkbox', label: 'Checkbox', value: 'checkbox' }];
+          alert.buttons = ['OK'];
+        </script>
+      `,
+        config
+      );
+
+      const ionAlertDidPresent = await page.spyOnEvent('ionAlertDidPresent');
+      const ionAlertDidDismiss = await page.spyOnEvent('ionAlertDidDismiss');
+      const alert = page.locator('ion-alert');
+
+      await alert.evaluate((el: HTMLIonAlertElement) => el.present());
+      await ionAlertDidPresent.next();
+
+      await alert.locator('.alert-button').press('Enter');
+      await ionAlertDidDismiss.next();
+
+      await expect(alert).toBeHidden();
+    });
+  });
+});
+
 /**
  * This behavior does not vary across directions
  */