Aligns short reads using dynamic seed size with strobemers
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Updated
Sep 9, 2026 - C++
Aligns short reads using dynamic seed size with strobemers
Long-read splice alignment with high accuracy
BLEND is a mechanism that can efficiently find fuzzy seed matches between sequences to significantly improve the performance and accuracy while reducing the memory space usage of two important applications: 1) finding overlapping reads and 2) read mapping. Described by Firtina et al. (published in NARGAB https://doi.org/10.1093/nargab/lqad004)
A Go implementation of the strobemers (https://github.com/ksahlin/strobemers)
Rust implementation of strobemer generation (MinStrobes, RandStrobes). Streaming iterators produce 64-bit strobemer hashes over DNA/RNA sequences.
Benchmarking pre-filtering large databases before short-read mapping
Rust implementation of alignment-free similarity estimation methods.
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